在某些情況下，MySQL的分組查詢（GROUP BY）可以替代子查詢，但并非所有情況都適用。下面是一些使用GROUP BY可以替代子查詢的場景：

1. 當需要對數據進行分組統計時，例如COUNT、SUM、AVG等聚合函數，可以使用GROUP BY進行分組查詢，而不需要子查詢。

SELECT department, COUNT(*) as num_employees
FROM employees
GROUP BY department;

這個查詢可以替代以下子查詢：

SELECT department, COUNT(*) as num_employees
FROM employees
WHERE department IN (SELECT department FROM employees);

2. 當需要根據某個字段的值進行分組排序時，可以使用GROUP BY結合ORDER BY進行排序，而不需要子查詢。

SELECT *
FROM employees
GROUP BY department
ORDER BY AVG(salary) DESC;

這個查詢可以替代以下子查詢：

SELECT *
FROM employees
WHERE department IN (SELECT department FROM employees GROUP BY department ORDER BY AVG(salary) DESC);

然而，在某些情況下，子查詢仍然是必要的，例如：

1. 當需要篩選出滿足特定條件的分組時，子查詢可以幫助我們先進行篩選，然后再進行分組。

SELECT department, COUNT(*) as num_employees
FROM employees
WHERE department IN (SELECT department FROM employees WHERE salary > 5000)
GROUP BY department;

2. 當需要對多個表進行連接查詢時，子查詢可以幫助我們先確定連接條件，然后再進行分組。

SELECT department, COUNT(*) as num_employees
FROM employees e
JOIN departments d ON e.department = d.department
WHERE d.manager_id IN (SELECT manager_id FROM employees WHERE salary > 5000)
GROUP BY department;

總之，雖然MySQL的分組查詢在某些情況下可以替代子查詢，但具體還需根據查詢需求和場景來判斷。